ERG/KCNH2 Polyclonal Antibody Sizes: 50µl, 100µl Catalogue Numbers: BS65805-50, BS65805-100 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Swiss-Prot: Q12809 Host: Rabbit Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, Applications: ICC, All Applications: ICC=1:100-500 Background: The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricular arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain. Purification and Purity: affinity purified by Protein A Storage and Stability: Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles. Specificity: ERG/KCNH2 Polyclonal Antibody detects endogenous levels of ERG/KCNH2 protein. Bioworld Molecular Weight: ~127 kDa Note: For research use only, not for use in diagnostic procedure. Extra Notes: Tissue/cell: MCF-7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min;Blocking buffer (normal goat serum, C-0005) at 37°C for 20 min; Antibody incubation with (ERG/KCNH2) Polyclonal Antibody, Unconjugated 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (5ug/ml, blue, C-0033) was used to stain the cell nuclei. Alternative Name: ERG; ERG1; H ERG; HERG 1; HERG; HERG1; LQT 2; LQT2; Potassium channel HERG; SQT1; Voltagegated potassium channel, subfamily H, member 2; KCNH2_HUMAN. Immunogen: KLH conjugated synthetic peptide derived from human HERG:1001-1159/1159 Conjugate: Unconjugated Modification: Unmodified