ERG/KCNH2 Polyclonal Antibody Sizes: 50μl, 100μl Catalogue Numbers: BS65805-50, BS65805-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: The potassium voltage gated channel, subfamily H (eag related), member 2 (KCNH2) gene encodes a voltage-gated potassium channel which has an important role in cardiac action potential repolarization in the mammalian heart. Mutations in KCNH2 have been shown to cause chromosome 7-linked congenital long QT syndrome, a disorder associated with delayed cardiac repolarization, prolonged electrocardiographic QT intervals, and the development of ventricμlar arrhythmias. KCNH2 channels are an important target for many drugs, and have emerged as a significant type of cardiac ion channel.Highly expressed in heart and brain. Category: Primary Antibody Reactivity: Human, Mouse, Rat, Dog, Pig, Horse, Rabbit Host: Rabbit Applications: ICC Alternate Names: ERG, ERG1, H ERG, HERG 1, HERG, HERG1, LQT 2, LQT2, Potassium channel HERG, SQT1, Voltagegated potassium channel, subfamily H, member 2, KCNH2_HUMAN. Clonality: Polyclonal Conjugate: Unconjugated Modification: Unmodification Immunogen: KLH conjugated synthetic peptide derived from human HERG:1001-1159/1159 Dilution: ICC=1:100-500 Purification: affinity purified by Protein A Specificity: ERG/KCNH2 Polyclonal Antibody detects endogenous levels of ERG/KCNH2 protein. Molecular Weight: ~127 kDa Storage and Stability: Store at 4°C short term. Aliquot and store at -22°C long term. Avoid freeze-thaw cycles. SwissProt: Q12809 Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Research Use Only