Product Description

ERG Rabbit Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS9883M-50, BS9883M-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P11308

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF, IHC

All Applications: WB: 1:1000
ICC/IF: 1:50-1:200
IHC: 1:50-1:200

Background: Defects in ERG are a cause of Ewing sarcoma (ES). A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors.

Purification and Purity: Protein A affinity purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of ERG and does not cross-react with related proteins.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of ERG Rabbit mAb at 1:1000 dilution
Lane 1: Jurkat whole cell lysate, Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-ERG antibody. Counter stained with hematoxylin., ICC staining ERG in PC-3M cells (green). The nuclear counter stain is DAPI (blue).Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton *100/PBS.

Alternative Name: Avian erythroblastosis virus E-26 (v-ets) oncogene related; D030036I24Rik; Erg 3; Erg; ERG/EWS fusion gene; included; ERG/FUS fusion gene; included; ERG/TMPSSR2 fusion gene; included; ERG; ERG1; included; ERG2; included; ets related; ETS-related gene; KCNH2; Oncogene ERG; p55; TMPRSS2/ERG fusion; Transcriptional regulator ERG; Transforming protein ERG; v ets avian erythroblastosis virus E26 oncogene; v ets avian erythroblastosis virus E26 oncogene related; v ets erythroblastosis virus E26

Immunogen: Recombinant antibody.

Conjugate: Unconjugated

Modification: Unmodified