ERK 2 Monoclonal Antibody
Size: 50μL, 100μL
Catalogue Numbers: RA10618-50, RA10618-100
Citations, Manuals and MSDS Available upon request.
Background: mitogen-activated protein kinase 1 (MAPK1) Homo sapiens This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reporte
Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol.
Storage Instructions: -20°C/1 year
Applications: WB; IHC-p; IF/ICC; ELISA
Species Cross-Reactivity: Human; Mouse; Monkey
GeneID (Human): 5594
SWISS: P28482
Source: Mouse
Research Use Only