Estrogen Receptor beta Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2546-20, A2546-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 59kDa
Observed Molecular Weight: 60kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 2100
SWISS: Q92731
Alternate Names: Erb; ESRB; ODG8; ESTRB; NR3A2; ER-BETA; ESR-BETA; Estrogen Receptor beta
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Nuclear hormone receptors, Cancer, Tumor biomarkers, Signal Transduction, MAPK-Erk Signaling Pathway, Endocrine Metabolism, Endocrine and metabolic diseases, Diabetes, Obesity, Neuroscience.
NCBI Alias: ESR2
Research Use Only