ET-1 rabbit pAb - ES3877

ET-1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3877-50, ES3877-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Alternate Name: EDN1; Endothelin-1; Preproendothelin-1; PPET1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 25kD

Human Gene ID: 1906

Human SWISS Prot NO: P05305

Subcellular Location: Secreted

Research Use Only