Ets-1 (phospho Ser251) rabbit pAb - ES5180

Ets-1 (phospho Ser251) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5180-50, ES5180-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],

Alternate Name: ETS1; EWSR2; Protein C-ets-1; p54

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Ets-1 (phospho Ser251)

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 2113

Human SWISS Prot NO: P14921

Subcellular Location: Cytoplasm. Nucleus. Delocalizes from nucleus to cytoplasm when coexpressed with isoform Ets-1 p27.

Research Use Only