EXD2 Polyclonal Antibody - E-AB-18841

EXD2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-18841-60, E-AB-18841-120, E-AB-18841-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: EXD2

Target Synonym: 4930539P14Rik; C14orf114; C85658; DKFZp781A0133; DKFZp781L15100; Exd2; EXD2; EXDL2; Exonuclease 3''-5'' domain-containing protein 2; Exonuclease 3''-5'' domain-like-containing protein 2; exonuclease 3'-5' domain-like 2; FLJ10738; RGD1311087

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB, IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q9NVH0

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Concentration: 0.96 mg/mL

Immunogen: Fusion protein of human EXD2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Calculated MW: 70 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only