Product Description

F7 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS72824-50, BS72824-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes coagμlation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circμlates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disμlfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagμlation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagμlopathy. Alternative splicing resμlts in mμltiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: F7, SPCA

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human F7(NP_062562.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Polyclonal Antibodies

Molecular Weight: 46kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P08709

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only