Product Description

FA10 (light chain, Cleaved-Arg179) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24788-50, RA24788-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: catalytic activity:Selective cleavage of Arg-|-Thr and then Arg-|-Ile bonds in prothrombin to form thrombin., function:Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting., online information:Factor X entry, PTM:N- and O-glycosylated., PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway)., PTM:The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains., PTM:The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium., similarity:Belongs to the peptidase S1 family., similarity:Contains 1 Gla (gamma-carboxy-glutamate) domain., similarity:Contains 1 peptidase S1 domain., similarity:Contains 2 EGF-like domains., subunit:The two chains are formed from a single-chain precursor by the excision of two Arg residues and are held together by 1 or more disulfide bonds., tissue specificity:Plasma; synthesized in the liver.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Coagulation factor X (EC 3.4.21.6;Stuart factor;Stuart-Prower factor) [Cleaved into: Factor X light chain, Factor X heavy chain, Activated factor Xa heavy chain]

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 15 53

Protein Molecular Weight (kDa): 15 53

Storage: -20°C/1 year

Human Gene ID: 2159

Human SwissProt Number: P00742

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only