Product Description

FA9 (light chain, Cleaved-Arg191) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24824-50, RA24824-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: coagulation factor IX (F9) Homo sapiens This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Coagulation factor IX (EC 3.4.21.22;Christmas factor;Plasma thromboplastin component;PTC) [Cleaved into: Coagulation factor IXa light chain, Coagulation factor IXa heavy chain]

Clonality: Polyclonal

Dilution: WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight: 16 45

Protein Molecular Weight (kDa): 16 45

Storage: -20°C/1 year

Human Gene ID: 2158

Human SwissProt Number: P00740

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only