Product Description

Factor XIIIa Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66006-50, MB66006-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Factor XIIIA, or fibrin stabilizing factor, is activated by thrombin and Ca2+ to a protransglutaminase in the final step of the blood coagμlation cascade that cross-links fibrin chains. This enzyme catalyzes the gamma-glutamyl-epsilon-lysine cross-linking between fibrin molecμles, stabilizing the fibrin clot. It is widely expressed in dermal dendritic cells. High expression of Factor XIIIA positive cells can be indicative of inflammatory conditions such as lichen planus and psoriasis.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: IHC

Alternate Names: F13A, Coagμlation factor XIII A chain, Coagμlation factor XIIIa, Protein-glutamine gamma-glutamyltransferase A chain, Transglutaminase A chain

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within human Factor XIIIa. The exact sequence is proprietary.

Dilution: IHC (1/100 - 1/300)

Purification: The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Recognizes endogenous levels of Factor XIIIa protein.

Molecular Weight: ~ 83 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P00488

Product: Mouse IgG2a. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.01% sodium azide.

Research Use Only