Product Description

FADD Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11188-50, RA11188-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Fas associated via death domain (FADD) Homo sapiens The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: FADD, FADD protein, FADD_HUMAN, Fas (TNFRSF6) associated via death domain, Fas associated via death domain, Fas associating death domain containing protein, Fas associating death domain containing protein, Fas associating protein, Fas associating protein with death domain, Fas associating protein with death domain, Fas TNFRSF6 associated via death domain, FAS-associated death domain protein, FAS-associating death domain-containing protein, FasTNFRSF6 associated via death domain, FasTNFRSF6 associated via death domain, GIG 3, GIG3, Growth inhibiting gene 3 protein, Growth-inhibiting gene 3 protein, H sapiens mRNA for mediator of receptor induced toxicity, H sapiens mRNA for mediator of receptor induced toxicity, Mediator of receptor induced toxicity, Mediator of receptor induced toxicity, MGC8528, MGC8528, MORT 1, MORT1, MORT1, Protein FADD.

Clonality: Monoclonal

Dilution: wb 1:500

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Human Gene ID: 8772

Protein Molecular Weight（KDa): 28

Molecular Weight: 28

Research Use Only