Product Description

FADD Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16882-50, BZ16882-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Apoptotic adaptor molecμle that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resμlting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC-P, ICC/IF, IP, FC

Alternate Names: FADD, MORT1, GIG3, Protein FADD, FAS-associated death domain protein, FAS-associating death domain-containing protein, Growth-inhibiting gene 3 protein, Mediator of receptor induced toxicity

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human FADD

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 FC: 1/50-1/100

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 23 kDa, Observed MW: 28 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13158

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Research Use Only