Product Description

FADD Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16883-50, BZ16883-100

Swiss-Prot: Q61160

Host: Rabbit

Reactivity: Mouse

Applications: WB, IHC-P, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100

Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Calculated MW: 23 kDa; Observed MW: 28 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FADD in Raw264.7 lysates using FADD antibody.

Alternative Name: FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1

Immunogen: A synthesized peptide derived from mouse FADD

Conjugate: Unconjugated

Modification: Unmodified