FADD Polyclonal Antibody
Product: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16883-50, BZ16883-100
Swiss-Prot: Q61160
Host: Rabbit
Reactivity: Mouse
Applications: WB, IHC-P, FC
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100
Background: Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Calculated MW: 23 kDa; Observed MW: 28 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of FADD in Raw264.7 lysates using FADD antibody.
Alternative Name: FADD protein; GIG3; Growth inhibiting gene 3 protein; Mediator of receptor induced toxicity; MORT1
Immunogen: A synthesized peptide derived from mouse FADD
Conjugate: Unconjugated
Modification: Unmodified