Product Description

FADD Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS45467-50, BS45467-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Apoptotic adaptor molecμle that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resμlting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regμlation of interferon signaling (By similarity).

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB, IHC, FC

Alternate Names: Mort1/FADD

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of mouse FADD

Dilution: WB: 1:1000-1:5000 IHC: 1:20-1:50 FC: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 28 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q61160

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only