Product Description

FAIM2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS62375-50, BS62375-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: FAIM2 (fas apoptotic inhibitory molecμle 2), also known as LFG (protein lifeguard), TMBIM2 (transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid mμltipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 resμlts in decreased caspase activation and reduced incidence of programmed cell death. Though mechanistically related to the Fas signal, FAIM2 does not protect cells from apoptosis that is mediated by TNF-α signaling. FAIM2 specifically regμlates apoptosis by binding to the FAS receptor.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Alternate Names: Protein lifeguard 2, Fas apoptotic inhibitory molecμle 2, Neural membrane protein 35, Transmembrane BAX inhibitor motif-containing protein 2, FAIM2, KIAA0950, LFG, LFG2, NMP35, TMBIM2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to Human FAIM2.

Dilution: WB:1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: FAIM2 polyclonal antibody detects endogenous levels of FAIM2 protein.

Molecular Weight: ~ 36 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9BWQ8

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only