Product Description

FAK (3D8) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3035-50, MB3035-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q05397

Host: Mouse

Reactivity: Human

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG1

Bioworld Molecular Weight: Calculated MW: 119 kDa; Observed MW: 125 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FAK in COS7, HUVEC, A549 and Hela lysates using FAK antibody., Immunofluorescence analysis of FAK in Hela using FAK antibody., Immunoprecipitation analysis of FAK in Hela lysates using FAK antibody.

Alternative Name: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Immunogen: Purified recombinant human FAK protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified