Product Description

FAK Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16437-50, BZ16437-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q05397

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 119 kDa; Observed MW: 119 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FAK in various lysates using FAK antibody., Western blot analysis of FAK in HT-29 lysates using FAK antibody., Immunohistochemistry analysis of paraffin-embedded Human brain tissue using FAK antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Western blot analysis of FAK in HeLa lysates treated with EGF using FAK antibody. The Lane on the right is blocked with the synthesized peptide.

Alternative Name: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK

Immunogen: The antiserum was produced against synthesized peptide derived from human FAK. AA range:373-422

Conjugate: Unconjugated

Modification: Unmodified