Product Description

FAM107A Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS76817-50, BS76817-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modμlating actin filamentous (F-actin dynamics. Mediates polymerization of globμlar actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regμlating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity. Plays a role in the actin and microtubμle cytoskeleton organization, negatively regμlates focal adhesion (FA assembly promoting malignant glial cell migration in an actin-, microtubμle- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimμlating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: FAM107A, DRR1, TU3A

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human FAM107A(NP_009108.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 18kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O95990

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only