FAM107A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-15012-60, E-AB-15012-120, E-AB-15012-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: FAM107A
Target Synonym: Down regulated in renal cell carcinoma 1; Down-regulated in renal cell carcinoma 1; Downregulated in renal cell carcinoma; DRR1; F107A; FAM107A; Family with sequence similarity 107; member A; FLJ30158; FLJ45473; Protein FAM107A; Protein TU3A; TU3A
Research Areas: Cancer, Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: O95990
Background: FAM107B is a 131 amino acid protein that is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.
Concentration: 0.5 mg/mL
Immunogen: Recombinant protein of human FAM107A
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only