Product Description

FARSLB Polyclonal Antibody

Catalogue Numbers: BS60426-50, BS60426-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q9NSD9

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: FARSLB (Phenylalanine--tRNA ligase beta chain), also known as FARSB, FRSB, PheHB or PheRS, is a 589 amino acid cytoplasmic protein that is the regulatory beta subunit of phenylalanine-tRNA synthetase. A highly conserved member of the aminoacyl-tRNA synthetase class IIc subfamily, FARSLB functions to enzymatically attach L-phenylalanine residues to terminal adenosines on tRNA(Phe). This is an ATP-dependent reaction that yields AMP, a diphosphate and an L-phenylalanine-tagged tRNA(Phe). FARSLB is expressed in brain, heart, kidney, pancreas, placenta and skeletal muscle and its expression is increased in malignant cell lines, suggesting a possible role for FARSLB in carcinogenesis.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FARSLB polyclonal antibody detects endogenous levels of FARSLB protein.

Extra Notes: Western blot (WB) analysis of FARSB pAb at 1:500 dilution
Lane1:CT-26 whole cell lysate(40ug)
Lane2:C6 whole cell lysate(40ug)
Lane3:PC3 whole cell lysate(40ug)
Lane4:EC9706 whole cell lysate(40ug)
Lane5:The pancreas tissue lysate of Mouse(40ug)
Lane6:U-87MG whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 80 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Phenylalanine--tRNA ligase beta subunit; Phenylalanyl-tRNA synthetase beta subunit; PheRS; FARSB; FARSLB; FRSB; HSPC173

Immunogen: A synthetic peptide corresponding to residues in Human FARSLB.

Conjugate: Unconjugated

Modification: Unmodified