FAT1 rabbit pAb - ES9143

FAT1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES9143-50, ES9143-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: Synthesized peptide derived from human protein . at AA range: 1140-1220

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 504kD

Human Gene ID: 2195

Human SWISS Prot NO: Q14517

Subcellular Location: [Protocadherin Fat 1]: Cell membrane; Single-pass type I membrane protein.; [Protocadherin Fat 1, nuclear form]: Nucleus.

Research Use Only