FAT2 rabbit pAb - ES11838

FAT2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11838-50, ES11838-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008],

Source: Rabbit

Applications: IHC; IF

Dilution: IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from part region of human protein

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 478kD

Human Gene ID: 2196

Human SWISS Prot NO: Q9NYQ8

Subcellular Location: Cell membrane; Single-pass type I membrane protein. Cell junction. Golgi apparatus trans-Golgi network. Localized at adhesion zippers (early state of adherens junctions) of keratinocytes.

Research Use Only