Product Description

FBL Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS6167-50, BS6167-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P22087

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, IHC, IF

All Applications: WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200

Background: Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FBL polyclonal antibody detects endogenous levels of FBL protein.

Bioworld Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: WesternBlot (WB) analysis of FBL polyclonal antibody in extracts from Hela, A375, U20S, COS1, COS7, PC12 cells and mouse brain, tesis tissues., Immunohistochemistry (IHC) analysis of FBL pAb in paraffin-embedded Human Breast Cancer tissue., Immunofluorescence analysis of Hela cells, using FBL polyclonal antibody

Alternative Name: 34 nucleolar scleroderma antigen; 34 a nucleolar scleroderma antigen; 34- nucleolar scleroderma antigen; FBL; FBRL; FIB; FIB1; FLRN; Nop1p; RNA U3 small nucleolar interacting protein 1; RNU3IP1; rRNA 2' O methyltransferase fibrillarin; rRNA 2'-O-methyltransferase fibrillarin;

Immunogen: Recombinant full length Human FBL.

Conjugate: Unconjugated

Modification: Unmodified