FBX32 Rabbit Polyclonal Antibody - RA32295

FBX32 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA32295-50, RA32295-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.66% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 114907

Protein MW (KDa): 38

SWISS: Q969P5

Source: Rabbit

Research Use Only