Product Description

FBXL18 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS9962M-50, BS9962M-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: FBL18 (F-box and leucine-rich repeat protein 18), also known as FBXL18, is an 805 amino acid protein that contains an F-box near its N-terminus, followed by several leucine-rich repeats and a transmembrane domain at the C-terminus. F-box proteins are critical components of the SCF (Skp1-Cμl-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. They are members of a larger family of proteins that are involved in the regμlation of a wide variety of cellμlar processes (including the cell cycle, immune response, signaling cascades and developmental processes) through the targeting of proteins, such as cyclins and cyclin-dependent kinase inhibitors (CDKNs), for degradation by the proteasome after ubiquitination.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, FC

Alternate Names: F-box/LRR-repeat protein 18, F-box and leucine-rich repeat protein 18, FBXL18, FBL18

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide corresponding to human FBXL18 aa 750 to C terminus.

Dilution: WB: 1:500
IHC: 1:50-1:200
FC: 1:50-1:100

Purification: Protein A affinity purified.

Specificity: This antibody detects endogenous levels of FBXL18 and does not cross-react with related proteins.

Molecular Weight: ~ 40, 88 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q96ME1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only