FBXW5 Rabbit Polyclonal Antibody - BT-AP10013

FBXW5 Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP10013-20, BT-AP10013-50, BT-AP10013-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the F-box protein family| members of which are characterized by an approximately 40 amino acid motif| the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box)| which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains| Fbls containing leucine-rich repeats| and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains| in addition to an F-box motif| so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene| however| they were found to be nonsense-mediated mRNA decay (NMD) candidates| hence not represented.

Research Areas: Epigenetics and nuclear signaling

Target Protein: FBXW5

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: FBXW5

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q969U6; Mouse: Q9QXW2; Rat: Q4KLI9

Synonyms: FBXW5; F-box/WD repeat-containing protein 5; F-box and WD-40 domain-containing protein 5)

GeneID: Human: 54461; Mouse: 30839; Rat: 362081

Research Use Only