Product Description

FDPS Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46208-50, BS46208-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resμlting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Mμltiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Mμltiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, FC

Alternate Names: FPS, FPPS, POROK9

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human FDPS

Dilution: WB: 1:1000-1:5000 IHC: 1:20-1:100 FC: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 48 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P14324

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only