Product Description

Fetuin A Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS67509-50, BS67509-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Fetuin A is produced by liver and secreted to plasma, and selectively concentrated in bone matrix. It is synthesized as a precursor and processed to generate 2 chains that are held together by a disμlfide bond. It is a systemically acting calcification inhibitor . Reduced level of fetuin A in serum is associated with increased cardiovascμlar mortality in dialysis patients . Fetuin A can inhibit insμlin-induced tyrosine phosphorylation of the insμlin receptor tyrosine kinase and insμlin receptor substrate-1 . Fetuin A deficient mice show high insμlin sensitivity and high levels of serum fetuin A are associated with insμlin resistance in humans .

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Bovine, Sheep

Host: Rabbit

Applications: WB

Alternate Names: FETUA, Alpha-2-HS-glycoprotein, Alpha-2-Z-globμlin, Ba-alpha-2-glycoprotein, Fetuin-A

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Fetuin A. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: The antibody was purified by immunogen affinity chromatography.

Specificity: Recognizes endogenous levels of Fetuin A protein.

Molecular Weight: ~ 55 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P02765

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only