Fetuin A Polyclonal Antibody-BS67509

Fetuin A Polyclonal Antibody

Catalogue Numbers: BS67509-50, BS67509-100

Sizes: 50µl, 100µl

Product: Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P02765

Host: Rabbit

Reactivity: Human, Mouse, Rat, Bovine, Sheep

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Fetuin A is produced by liver and secreted to plasma, and selectively concentrated in bone matrix. It is synthesized as a precursor and processed to generate 2 chains that are held together by a disulfide bond. It is a systemically acting calcification inhibitor . Reduced level of fetuin A in serum is associated with increased cardiovascular mortality in dialysis patients . Fetuin A can inhibit insulin-induced tyrosine phosphorylation of the insulin receptor tyrosine kinase and insulin receptor substrate-1 . Fetuin A deficient mice show high insulin sensitivity and high levels of serum fetuin A are associated with insulin resistance in humans .

Purification and Purity: The antibody was purified by immunogen affinity chromatography.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of Fetuin A protein.

Extra Notes: Western blot analysis of Fetuin A expression in PC12 (A), AML12 (B), HEK293T (C), H1792 (D) whole cell lysates.

Bioworld Molecular Weight: ~ 55 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: FETUA; Alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Fetuin A. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified