Product Description

FGA Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB66776-50, MB66776-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: α, β and γ. Fibrinogen is important in platelet aggregation, the final step of the coagμlation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagμlants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagμlation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascμlar injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regμlate cell adhesion and spreading, display vasoconstrictor and chemotactic activities and are mitogens for several cell types.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Mouse

Applications: WB

Alternate Names: Fibrinogen alpha chain

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human FGA. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of FGA protein.

Molecular Weight: ~ 140 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P02671

Product: Mouse IgM. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only