FGF2 Polyclonal Antibody - E-AB-67281

FGF2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-67281-60, E-AB-67281-120, E-AB-67281-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FGF2

Target Synonym: BFGF; FGF-2; FGFB; HBGF-2; Basic FGF; FGF2

Research Areas: Cancer, Cardiovascular, Developmental Biology, Neuroscience, Signal Transduction, Stem Cells

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P09038

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Concentration: 1mg/mL

Immunogen: Recombinant protein of human FGF2.

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 22kDa/24kDa

Observed MW: 22kDa/24kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only