Product Description

FGFR1/2/3/4 (Phospho-Tyr653+Tyr654) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36826-50, RA36826-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: fibroblast growth factor receptor 1 (FGFR1) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome,

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)

Clonality: Polyclonal

Dilution: WB 1:500-2000

Storage: -20°C/1 year

Human Gene ID: 2260

Human SwissProt Number: P11362

Condition: Liquid in PBS containing 50% glycerol, and 0.142% sodium azide.

Research Use Only