FGFR2 (Phospho-Tyr769) Rabbit Polyclonal Antibody - RA36813

FGFR2 (Phospho-Tyr769) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36813-50, RA36813-100

Citations, Manuals and MSDS Available upon request.

Background: fibroblast growth factor receptor 2 (FGFR2) Homo sapiens The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, C

Condition: Liquid in PBS containing 50% glycerol, and 0.128% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Fibroblast growth factor receptor 2 (FGFR-2) (EC 2.7.10.1) (K-sam) (KGFR) (Keratinocyte growth factor receptor) (CD antigen CD332)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2263

SWISS: P21802

Source: Rabbit

Research Use Only