Product Description

FGFR2 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS90507-50, BS90507-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P21802(Human) P21803(Mouse) EntrezGene:25022(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB IP

All Applications: WB:1:1,000-1:2,000
IP:1:10-1:50

Background: Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. These include the Flg receptor or FGFR-1, the Bek receptor (or FGFR-2), FGFR-3, FGFR-4, FGFR-5 and FGFR-6. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. The gene encoding human Bek (also designated K-sam) maps to chromosome 10q26.13 and is alternatively spliced to produce several isoforms. Heterogeneous mutations in Bek are associated with a range of craniosynostosis syndromes including Pfeiffer syndrome, Crouzon syndrome, Jackson-Weiss syndrome and Apert syndrome..

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FGFR2 on different cellLysates using anti-PGFR2 antibody at 1/1,000 dilution. Positive control: Lane 1:MCF-7 Lane 2: Jurkat

Bioworld Molecular Weight: 145 kDa

Specificity: FGFR2 polyclonal antibody detects endogenous levels of FGFR2 protein.

Alternative Name: FGFR-2, KGFR, FGFR2, bacteria-expressed kinase, BBDS, BEK, BEK fibroblast growth factor receptor, BFR1, CD332, CD332 antigen, CEK3, CFD1, Craniofacial dysostosis 1, ECT1, FGF receptor, FGFR 2, FGFR-2, Fgfr2, FGFR2, Fibroblast growth factor receptor 2, Hydroxyaryl protein kinase, Jackson Weiss syndrome, JWS, K SAM, K-sam, Keratinocyte growth factor receptor 2, Keratinocyte growth factor receptor, KGFR, KSAM, protein tyrosine kinase, receptor like 14, soluble FGFR4 variant 4, TK14, TK25,

Immunogen: recombinant protein

Conjugate: Unconjugated

Modification: Unmodified