FGFR3 (Phospho-Tyr724) Rabbit Polyclonal Antibody - RA36784

FGFR3 (Phospho-Tyr724) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA36784-50, RA36784-100

Citations, Manuals and MSDS Available upon request.

Background: fibroblast growth factor receptor 3 (FGFR3) Homo sapiens This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dys

Condition: Liquid in PBS containing 50% glycerol, and 0.95% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000

Alternative Names: Fibroblast growth factor receptor 3 (FGFR-3) (EC 2.7.10.1) (CD antigen CD333)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2261

SWISS: P22607

Source: Rabbit

Research Use Only