Product Description

FGFR3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65742-50, BS65742-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: P22607

Host: Rabbit

Reactivity: Human, Mouse, Rat,Chicken,Dog, Cow, Horse, Sheep,

Applications: WB

All Applications: WB=1:500-2000

Background: The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FGFR3 Polyclonal Antibody detects endogenous levels of FGFR3 protein.

Bioworld Molecular Weight: 101 kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary: Anti-FGFR3 at 1/500 dilution

Alternative Name: ACH; CD 333; CD333; CD333 antigen; CEK 2; CEK2; FGFR 3; Fibroblast growth factor receptor 3 (achondroplasia thanatophoric dwarfism); Fibroblast growth factor receptor 3; Heparin binding growth factor receptor; HSFGFR3EX; Hydroxyaryl protein kinase; JTK 4; JTK4; MFR 3; SAM 3; Tyrosine kinase JTK 4; Tyrosine kinase JTK4; Z FGFR 3; FGFR3_HUMAN.  

Immunogen: KLH conjugated synthetic peptide derived from human FGFR3:501-600/801 

Conjugate: Unconjugated

Modification: Unmodified