Product Description

FGG Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-40412-60, E-AB-40412-120, E-AB-40412-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: FGG

Target Synonym: FGG; Fibrinogen gamma chain; Fibrinogen gamma polypeptide

Research Areas: Cardiovascular

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, IHC

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8VCM7

Background: The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

Concentration: 1mg/mL

Immunogen: Recombinant Mouse Fibrinogen gamma chain protein

Buffer: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.

Purification Method: Antigen Affinity Purification

Dilution: WB 1:1000-1:3000 IHC 1:100-1:300

Calculated MW: 49 kDa

Observed MW: 49 kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only