Product Description

FIBP Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8216-50, BS8216-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43427

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: Fibroblast growth factors (FGFs) represent a family of over twenty distinct proteins that are ubiquitously expressed in mammalian systems. FGF activity influences development, adult tissue homeostasis, angiogenesis and cancer progression. The FGF-1 intracellular-binding protein (FIBP) is a 364 amino acid protein that binds to internalized FGF-1 and is thought to be involved in mitogenic function of FGF-1. FIBP localizes to the nucleus and is highly expressed in heart, skeletal muscle and pancreas and at lower levels in brain, placenta, liver and kidney. The gene encoding FIBP is expressed as two isoforms, designated long and short, which are produced as a result of alternative splicing events.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: FIBP polyclonal antibody detects endogenous levels of FIBP protein.

Bioworld Molecular Weight: ~ 42 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot (WB) analysis of FIBP polyclonal antibody

Alternative Name: Acidic fibroblast growth factor intracellular-binding protein; aFGF intracellular-binding protein; FGF-1 intracellular-binding protein; FIBP

Immunogen: Recombinant full length Human FIBP.

Conjugate: Unconjugated

Modification: Unmodified