Fibulin-4 rabbit pAb - ES5708

Fibulin-4 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5708-50, ES5708-100

Citations, Manuals and MSDS Available upon request.

Background: A large number of extracellular matrix proteins have been found to contain variations of the epidermal growth factor (EGF) domain and have been implicated in functions as diverse as blood coagulation, activation of complement and determination of cell fate during development. The protein encoded by this gene contains four EGF2 domains and six calcium-binding EGF2 domains. This gene is necessary for elastic fiber formation and connective tissue development. Defects in this gene are cause of an autosomal recessive cutis laxa syndrome. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011],

Alternate Name: EFEMP2; FBLN4; EGF-containing fibulin-like extracellular matrix protein 2; Fibulin-4; FIBL-4; Protein UPH1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from human EFEMP2. AA range:91-140

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 50kD

Human Gene ID: 30008

Human SWISS Prot NO: O95967

Subcellular Location: Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, extracellular matrix, basement membrane. Localizes on the microfibrils surrounding ELN cores.

Research Use Only