FIG4 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA24966-50, RA24966-100
Citations, Manuals and MSDS Available upon request.
Background: FIG4 phosphoinositide 5-phosphatase (FIG4) Homo sapiens The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: WB 1:500-2000, ELISA 1:10000-20000
Alternative Names: Polyphosphoinositide phosphatase (EC 3.1.3.-) (Phosphatidylinositol 3,5-bisphosphate 5-phosphatase) (SAC domain-containing protein 3)
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse
GeneID (Human): 9896
Protein MW (KDa): 110
SWISS: Q92562
Source: Rabbit
Research Use Only