Product Description

FIR Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA24971-50, RA24971-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton., similarity:Contains 1 DH (DBL-homology) domain., similarity:Contains 1 FERM domain., similarity:Contains 2 PH domains., subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.,

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF/ICC, ELISA

Alternate Names: FARP2, KIAA0793, PLEKHC3, FERM, RhoGEF and pleckstrin domain-containing protein 2, FERM domain including RhoGEF, FIR, Pleckstrin homology domain-containing family C member 3, PH domain-containing family C member 3

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 119

Protein Molecular Weight (kDa): 119

Storage: -20°C/1 year

Human Gene ID: 9855

Human SwissProt Number: O94887

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only