FLI1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A5644-20, A5644-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t (11;22) (q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t (4;11) (q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IP, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 51kDa
Observed Molecular Weight: 51kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 2313
SWISS: Q01543
Alternate Names: EWSR2; FLI-1; SIC-1; BDPLT21; FLI1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cancer, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Endocrine Metabolism.
NCBI Alias: FLI1
Research Use Only