Fliz1 Polyclonal Antibody - BT-AP03268

Fliz1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03268-20, BT-AP03268-50, BT-AP03268-100

Citations, Manuals and MSDS Available upon request.

Background: ZC3H8 is a Protein Coding gene. Zinc finger CCCH domain-containing protein 8 acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity). Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780). Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. Among its related pathways are Gene Expression and RNA Polymerase II Transcription Initiation And Promoter Clearance. GO annotations related to this gene include poly (A) RNA binding and sequence-specific DNA binding. An important paralog of this gene is ZC3H4.

Research Areas: Epigenetics and Nuclear Signaling

Target Protein: ZC3H8

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Fliz1 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 33576

UniProt Accession: Human: Q8N5P1; Mouse: Q9JJ48

Synonyms: ZC3H8; ZC3HDC8; Zinc finger CCCH domain-containing protein 8

GeneID: Human: 84524

Research Use Only