FMR1 Monoclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA11234-50, RA11234-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: fragile X mental retardation 1 (FMR1) Homo sapiens The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010], Reactivity: Human Host: Mouse Applications: WB, IHC-p, IF/ICC, ELISA Alternate Names: FMR1, Fragile X mental retardation protein 1, FMRP, Protein FMR-1 Clonality: Monoclonal Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications. Storage: -20°C/1 year Condition: Ascitic fluid containing 0.03% sodium azide, 0.5% BSA, 50% glycerol. Human Gene ID: 2332 Research Use Only