FMRP Monoclonal Antibody-MB10251

FMRP Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10251-50, MB10251-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q06787

Host: Rabbit

Reactivity: Human, Monkey

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 71 kDa; Observed MW: 70-80 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FMRP in 293, U2OS, Jurkat, COS7 lysates using FMRP antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using FMRP antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of FMRP in Hela using FMRP antibody, and DAPI

Alternative Name: FMR1; Fragile X mental retardation protein 1; FMRP; Protein FMR-1

Immunogen: A synthetic peptide of human FMRP

Conjugate: Unconjugated

Modification: Unmodified