Product Description

FNDC5 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB67152-50, MB67152-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Fibronectins are mμlti-domain glycoproteins that bind to a variety of substances including collagen, Actin, heparin, DNA, fibrin and Fibronectin receptors. They are involved in a diverse array of important functions such as blood coagμlation, wound healing, cell adhesion, cell differentiation and migration. FNDC5 (Fibronectin type III domain containing 5), also known as FRCP2, is a 196 amino acid single-pass type I membrane protein that is imported in peroxisomes through the Peroxin 5 receptor pathway. Existing as four alternatively spliced isoforms, FNDC5 is encoded by a gene located on human chromosome 1p35.1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.

Category: Primary Antibody

Reactivity: Human

Host: Mouse

Applications: WB

Alternate Names: FRCP2, Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FNDC5. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of FNDC5 protein.

Molecular Weight: ~ 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8NAU1

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only