Product Description

FOLH1 Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB67306-25, MB67306-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resμlting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regμlated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to mμltiple transcript variants encoding several different isoforms.

Category: Primary Antibody

Reactivity: Human, Rat

Host: Mouse

Applications: WB, IF, ELISA

Alternate Names: FGCP, FOLH, GCP2, GCPII, mGCP, NAALAD1, NAALAdase, PSM, PSMA

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Fμll length human recombinant protein of human FOLH1(NP_004467) produced in HEK293T cell.

Dilution: WB 1:500~2000, IF 1:100

Purification: Purified from mouse ascites fluids or tissue cμlture supernatant by affinity chromatography (protein A/G)

Specificity: FOLH1 mouse monoclonal antibody detects endogenous levels of FOLH1 protein.

Molecular Weight: ~ 89 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q04609

Product: PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Research Use Only