Product Description

FOXA1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10931-50, MB10931-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P55317

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: Forkhead box protein A1 is a transcription factor required for the development of endoderm-derived organs, such as liver, lung, and prostate. FoxA1 functions as a pioneer factor that is recruited primarily to the distant enhancers to change chromatin structure for transcription in a cell type-specific manner. Involved in regulation of apoptosis by inhibiting the expression of BCL2. Involved in cell cycle regulation by activating expression of CDKN1B, alone or in conjunction with BRCA1.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 49 kDa; Observed MW: 49 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FOXA1 in T47D lysates using FOXA1 antibody., Western blot analysis of FOXA1 in C6 lysates using FOXA1 antibody., Immunocytochemistry analysis of FOXA1 in MCF-7 using FOXA1 antibody, and DAPI

Alternative Name: FOXA1; Forkhead box A1; Forkhead box protein A1; HNF-3-alpha; TCF3A; HNF3A; Transcription factor 3A

Immunogen: Recombinant protein of human FOXA1

Conjugate: Unconjugated

Modification: Unmodified