Product Description

FoxK1 (G698) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS2293-50, BS2293-100

Sizes: 50µl, 100µl

Swiss-Prot: P85037

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predominantly expressed in many malignant tissues, such as tumors of the brain, colon and lymph node.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: FoxK1 (G698) polyclonal antibody detects endogenous levels of FoxK1 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of FoxK1 (G698) pAb at 1:500 dilution
Lane 1: K562 whole cell lysate (40ug)
Lane 2: HCT116 whole cell lysate (40ug)
Lane 3: A549 whole cell lysate (40ug)
Lane 4: MCF-7 whole cell lysate (40ug)
Lane 5: CT26 whole cell lysate (40ug)
Lane 6: C6 whole cell lysate (40ug), Immunohistochemistry (IHC) analyzes of FoxK1 (G698) pAb in paraffin-embedded human breast carcinoma tissue at 1:100.

Bioworld Molecular Weight: ~ 75, 97 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: FHX; Fork head; Forkhead box protein K1; FOXJ2 forkhead factor; FOXK1; FOXK1; MNF; Myocyte nuclear factor;

Immunogen: Synthetic peptide, corresponding to amino acids 668-720 of Human FoxK1.

Conjugate: Unconjugated

Modification: Unmodified