Product Description

FOXO1 Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16359-50, BZ16359-100

Swiss-Prot: Q12778

Host: Rabbit

FOXO1 Polyclonal Antibody-BZ16359

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Pig

Applications: WB, IHC-F, IHC-P, ICC/IF, ELISA, ChIP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ChIP: 1/20 ELISA: 1/10000

Background: Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 70 kDa; Observed MW: 78 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of FoxO1 in CHO-K1, C6 and HelaLysates using FoxO1 antibody., ChIPPCR detected the FoxO1 binding sites in the AdipoQ promoter region.

Alternative Name: FOXO1; FKHR; FOXO1A; Forkhead box protein O1; Forkhead box protein O1A; Forkhead in rhabdomyosarcoma

Immunogen: The antiserum was produced against synthesized peptide derived from human FKHR. AA range:223-272

Modification: Unmodified

Conjugate: Unconjugated